Freeze-Dried Plasma

My nerdy interest du jour is battlefield medicine, tactical combat casualty care and field medicine (the non-military side of emergency medicine, used in disaster relief). The concept of triage and how to tackle logistical hurdles such as how to carry or transport sensitive equipment and items that need special storage (like refrigeration or freezing) in sparse or hostile environments is fascinating! I just ordered Battlefield Angels: Saving Lives Under Enemy Fire From Valley Forge to Afghanistan on my Kindle and can’t wait to dive into it (just have to finish A Feast for Crows first…)

I started thinking about the topic because an article in caught my eye: U.S. Army backs Vascular Solutions’ freeze-dried plasma push.

Freeze-dried… freeze-dried plasma. For transfusion. Woah. We can do that?

Plasma is the part of the blood that does not include red blood cells (erythrocytes). You can draw a tube of blood from someone, spin it in a centrifuge, and separate the different components of blood:

cartoon of a test tube of whole blood that has been centrifuged into red blood cells, white blood cells and platelets, and plasma)

Plasma is useful for transfusions in the case of blood loss. Plasma contains water, clotting factors and other proteins, and in the case of traumatic injury and blood loss, these properties can help keep a patient’s blood volume at proper levels so that blood pressure is maintained and the right proteins are in sufficient supply. Patients in the field may need plasma, red blood cells or transfusions of other specific components. Transfusion medicine is a huge and independent field of study. And again: flippin’ fascinating.

According to the infallible source of knowledge that is Wikipedia, the military has been using dried plasma since 1918, which – woah – I did not know, but it makes a sense that a solution was found early on to the challenge of carrying around a heavy liquid that takes up space and is susceptible to degradation. Plasma is mostly water, so dried plasma + water = transfusable plasma that stayed fresh for up to four hours.1

But different situations – environment and available resources, for example – call for different solutions. And even as late as the 1990s military surgical teams have carried units of RBCs on ice, and blood bags for the collection of fresh whole blood from soldiers if plasma or platelets were needed.2

Another cool bit of information that I’ve come across: it’s possible to transfuse too much blood. If someone has an injury and is bleeding internally, it don’t do no good to keep giving ’em fluids; they’ll just leak it out into the area around the wound, which puts them in a more critical condition. You can also have dilutional coagulopathy (in which you dilute out the patient’s platelets and clotting factors – seen in platelet-depleted RBC transfusions – they can’t clot and so can’t stop bleeding), you can put various electrolytes out of balance, cause lung injury, have donor-recipient antibody incompatibilities, and that’s all assuming you’ve already matched your donors and screened out units that contain the common transfusion-transmitted viruses!

But back to field medicine – we can freeze-dry plasma. Woah. Science is cool.

Freeze-Dried Plasma

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    From packaging your hand bags appropriately and boarding your trip to exchanging your hard earned money and finding the right locations to nibble on and sleep at night in another country, travelling can rapidly become a extremely complex business. Be sure you approach vacationing with the information necessary to move your journey off without a problem. Read this article to learn how. Establish a budget for the travel expedition prior to your leaving. It really is so simple to spend too much when you find yourself during a trip great and you also aren’t taking into consideration the realities or outcomes in the funds you might be investing. Identifying a budget ahead of time and sticking with it is going to make sure that you can afford to adopt potential holidays. When choosing a vacation spot, be sure you understand the lay of your property before heading. You can do some investigation on the internet or ask folks you know, who definitely have gone to the specific spot that you may be going to. When you have a solid idea of what you should do at your location, even before you arrive there, it may help the entire journey experience being a lot smoother. When you have a notebook computer, deliver an A/V cable along with you on your own vacation. Most rooms in hotels come provided with a tv, and a lot of now involve cost-free wi-fi as well. By hooking your notebook computer up to the resort television by having an A/V cable television you immediately get access to many more enjoyment possibilities, whether streaming a motion picture from the internet to making use of the laptop as being a DVD participant. To help relive stress, it is important to take a getaway from job. Taking place a yearly vacation will provide you with some thing to be effective challenging for and will also give you a light-weight after the tunnel. You should treat yourself and there is no far better incentive compared to a trip! If you choose to purchase journey insurance coverage well before having a getaway, you would probably do well to acquire it from an independent resource. Let’s say you reserve a cruise trip and they are provided journey insurance through the cruise trip firm. Since you are essentially purchasing security against the luxury cruise line’s own errors/accidents, it can make more sense to purchase your insurance from some other source rather than to count on the possible reason behind your long term declare when your insurance company. Mentioned previously just before, there is certainly nothing more fun than planing a trip to new places. Though travelling provides you many new and enjoyable activities, there are several stuff you need to understand ahead of time. By utilizing the tips that were presented in this post, you could have probably the most pleasurable time while traveling.

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    Though traveling country wide or worldwide provides you with the chance to begin to see the world and interact with individuals of most backgrounds, it could also be a hassle, an cost or perhaps a threat. However, you can make the vacation a lot less demanding plus more enjoyable, no matter if it’s for enterprise or enjoyment. All you need to do is comply with these simple tips. When choosing a destination for your trips, maintain abrest of the current reports. Deciding on spots that happen to be in substantial levels of struggle might not be the ideal thought. Even so, don’t permit over-concerned relatives and friends chat you of a trip to a safe and secure spot which has recently been the victim of some sort of invasion. Be sure you possess a package water along. No matter if you find on your own out in the wilderness or even in a vibrant metropolis, having a container of water on your own man or woman always is never a bad strategy. They are specifically an easy task to always keep useful when you possess a purse. Scout out vouchers and deals. Before you decide to set off of to your vacation spot, execute a thorough Online search for destination and cafe discount rates. On a monthly basis or two before leaving, sign up to the local discounts display site to your vacation spot to rating some terrific savings. Also you can look into buying a promotion book to your spot. Look at coupons it has and determine if the price of the book may well be more than made in the money you’ll help save. Conserve a pleased mindset while on a trip. Issues could get somewhat stressed at international airports. Tempers manage high. The people who job there usually find it difficult of stuff. Keeping an optimistic demeanor of you, at the very least outwardly, will likely boost your encounter. A poor perspective will almost never get you just about anywhere. Anticipation will develop the second you guide a trip. With all the appropriate assistance, you are able to avoid the a lot of issues that watch for the unskilled vacationer. Hopefully these guidelines can help you assembled the perfect strategy so that you can know your journey dream.

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    Its like you read my mind! You seem to know a lot about this, like you wrote the book in it or something. I think that you could do with a few pics to drive the message home a little bit, but other than that, this is excellent blog. A fantastic read. I will certainly be back.

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    Discretion traveling is a marvellous encounter that everyone needs to have within their life. Even organization journey can be created pleasurable. There are some aspects of journey that may detract from your satisfaction. After the suggestions in this post could assist you in getting most from any trip that you could will need or would like to consider. There are tons of possibilities in relation to journey today. If you are intending a trip to a region you possess never ever been to prior to, you really should meet with a skilled tour operator. They can alert you to any special information you will need for example customs, weather conditions patters, and essential vaccinations. Question a family member or friend to drive one to the airport. You save on cab fare and lasting vehicle parking service fees. Many individuals will be happy to perform this favour for you, particularly if are likely to reciprocate down the road down the road, while they are going for a vacation. A single ingredient that might not exactly come to mind immediately when organizing journey is climate. By searching for the climate forecast before travelling, or perhaps before figuring out when you should vacation you might know what you should expect. If the conditions appearance bad, it can be prepared for or perhaps the getaway even rescheduled. When you are vacationing through a small airport, check out their webpage to view each and every flight that they can support. Many of them will offer charter air flights that you can’t see when you are evaluating offers, and so they could possibly allow you to get a great price. Idea your concierge! Whether it be on a cruise or with a resort, your concierge will probably be your go-to guy for reservations, directions and just about everything in addition! A lot of concierges have accepted that when somebody is happy to suggestion them effectively, they will likely go out of their way to ensure those fantastic tippers, have got a fantastic time. Since you now have learned a bit about how to streamline the procedure of vacationing on this page, it’s time to proceed to start off organizing that vacation. No matter if you’re checking out far-away areas or simply soaring across the nation, you have to be well informed for virtually any getaway you practice.

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    You must make sure that you just prepare your holiday before hand, whether you are touring for enjoyment or operate. Keep reading for many tips. When deciding on a destination to travel to pick someplace that is certainly inexpensive. You don’t want to travel anywhere which is so pricey you can’t enjoy yourself towards the fullest. You desire to make sure you enjoy yourself, but as well, you want to ensure it is match your financial allowance. Pack some plastic-type material totes when going on a lengthier getaway. Plastic-type hand bags generally come in useful if you drip one thing, for toiletries or if you have some filthy washing. In the mean time, some places have laundry prospects, so it will be constantly helpful to have a plastic-type bag with you to maintain your filthy laundry washing in. Remote regions tend to be amongst the most interesting of achievable holiday destinations. Just be sure you have requirements just like your medication medications along with you. Just one way of considering it is that if one thing isn’t on the market your location then you probably didn’t need it in any case! Items like prescription drugs, nevertheless, may be vital so don’t leave getting them to chance. When traveling by using an plane, make certain to get all you would require for the next working day in your maintain. Because your keep on is always along with you, you can be assured that if they will likely loose your suitcases that you are able to get by on the very next day. In many instances, airlines ought to have your travel luggage for your needs by then. Following the straightforward suggestions given earlier mentioned, you will notice that your vacation adventures become much easier. With these ideas it is possible to totally chill out and appreciate your holidays understanding that your travel programs will go away from without a hitch. This advice will help you appreciate stress-cost-free traveling, causing you to be able to take pleasure in the places you’re browsing.

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    Hey there! I know this is somewhat off topic but I was wondering which blog platform are you using for this site? I’m getting fed up of WordPress because I’ve had issues with hackers and I’m looking at options for another platform. I would be fantastic if you could point me in the direction of a good platform.

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    Fantastic blog! Do you have any helpful hints for aspiring writers? I’m planning to start my own blog soon but I’m a little lost on everything. Would you recommend starting with a free platform like WordPress or go for a paid option? There are so many choices out there that I’m completely confused .. Any recommendations? Thank you!

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    This design is steller! You most certainly know how to keep a reader amused. Between your wit and your videos, I was almost moved to start my own blog (well, almost…HaHa!) Excellent job. I really loved what you had to say, and more than that, how you presented it. Too cool!