My nerdy interest du jour is battlefield medicine, tactical combat casualty care and field medicine (the non-military side of emergency medicine, used in disaster relief). The concept of triage and how to tackle logistical hurdles such as how to carry or transport sensitive equipment and items that need special storage (like refrigeration or freezing) in sparse or hostile environments is fascinating! I just ordered Battlefield Angels: Saving Lives Under Enemy Fire From Valley Forge to Afghanistan on my Kindle and can’t wait to dive into it (just have to finish A Feast for Crows first…)
I started thinking about the topic because an article in bizjournal.com caught my eye: U.S. Army backs Vascular Solutions’ freeze-dried plasma push.
Freeze-dried… freeze-dried plasma. For transfusion. Woah. We can do that?
Plasma is the part of the blood that does not include red blood cells (erythrocytes). You can draw a tube of blood from someone, spin it in a centrifuge, and separate the different components of blood:
Plasma is useful for transfusions in the case of blood loss. Plasma contains water, clotting factors and other proteins, and in the case of traumatic injury and blood loss, these properties can help keep a patient’s blood volume at proper levels so that blood pressure is maintained and the right proteins are in sufficient supply. Patients in the field may need plasma, red blood cells or transfusions of other specific components. Transfusion medicine is a huge and independent field of study. And again: flippin’ fascinating.
According to the infallible source of knowledge that is Wikipedia, the military has been using dried plasma since 1918, which – woah – I did not know, but it makes a sense that a solution was found early on to the challenge of carrying around a heavy liquid that takes up space and is susceptible to degradation. Plasma is mostly water, so dried plasma + water = transfusable plasma that stayed fresh for up to four hours.1
But different situations – environment and available resources, for example – call for different solutions. And even as late as the 1990s military surgical teams have carried units of RBCs on ice, and blood bags for the collection of fresh whole blood from soldiers if plasma or platelets were needed.2
Another cool bit of information that I’ve come across: it’s possible to transfuse too much blood. If someone has an injury and is bleeding internally, it don’t do no good to keep giving ’em fluids; they’ll just leak it out into the area around the wound, which puts them in a more critical condition. You can also have dilutional coagulopathy (in which you dilute out the patient’s platelets and clotting factors – seen in platelet-depleted RBC transfusions – they can’t clot and so can’t stop bleeding), you can put various electrolytes out of balance, cause lung injury, have donor-recipient antibody incompatibilities, and that’s all assuming you’ve already matched your donors and screened out units that contain the common transfusion-transmitted viruses!
But back to field medicine – we can freeze-dry plasma. Woah. Science is cool.
3,488 thoughts on “Freeze-Dried Plasma”
I don’t believe I’ve ever heard that. Way cool!
I was expecting cool physics, but instead I got cool biology. Not disappointed!
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Freeze-drying is fun to watch, especially a demonstration where you put an ordinary bowl of tap water in the machine and bring the pressure down. Watching the water simultaneously boil and freeze is a show-stopper.
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Vacationing doesn’t must be a large task. If you have the correct steps into position and knowledge about what you can do and what to consider, you are able to be a experienced travel professional right away. This information will look into the kinds of things that you have to know, to become prepared for all of your trips. Get local choices online while you are travelling. You can find frequently many restaurants situated about hotels. In case you have an internet connection your location remaining, make use of it to check them up on the web. Often you can find menus on the websites. You will also find directions and pertinent evaluations. In case you have allergic reactions to cats, dogs or perhaps dust particles, you ought to provide your allergic reaction treatments with you about the aeroplane. Individuals often provide their creatures together on air flights. Even if your wildlife isn’t associated them on the vacation, they continue to have animal pollen on their own outfits. Perform some research in advance and check out cusine credits and discount coupons to your location. You may also help save a lot of money by permitting advice about where you should eat prior to leave. This is better than looking for suggestions when you are already feeling hungry and in a strange location. For several the road getaway is the only way to travel. If you’re will be going for a street getaway do that straightforward issues in advance therefore you don’t wind up stranded half way country wide. Number 1, make sure to get an oils modify! Number two, have your auto mechanic give your car or truck a once over prior to depart. The worst thing you need during no exactly where are typically avoidable mechanized failures. Tip your concierge! Whether it be over a cruise trip or in a resort, your concierge will be your go-to man for bookings, guidelines and almost anything different! Several concierges have accepted when a person is happy to suggestion them properly, they will likely get out of their way to make sure all those excellent tippers, use a great time. There is no need to concern yourself with obtaining dropped yet again if you are vacationing if you keep to the recommendations which have been offered in the following paragraphs. You need to be accountable while you are traveling and make sure that you might be not proceeding anywhere that you really usually do not need to be.
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